In 2009, Quake made headlines when he sequenced his own genome for under $50,000 using a single machine, helping usher in an era of personalized medicine in which an individual’s genetic information can guide diagnosis and treatment. The company generated sales of $10.8 million in the first quarter of 2012. He co-founded Fluidigm Corp in 1999 to commercialize the technology. Quake developed a chip with miniature pumps and valves that incorporates complex fluid-handling steps to speed genetic research. “Often I find the measurement technique has different applications.” “I get interested in a scientific problem and often find a way to measure the thing I’m interested in,” Quake said in an interview.
Quake, a professor of bioengineering and applied physics at Stanford University and investigator at the Howard Hughes Medical Institute, has applied the technological principles of the integrated circuit - a chip made of semiconductor material found in almost every modern electrical device - to biology. Quake, a prolific inventor whose creative application of physics to biology has lead to multiple developments in drug discovery and genome analysis, has won the prestigious $500,000 Lemelson-MIT prize for outstanding innovators. Inventor, physicist and entrepreneur Dr Stephen Quake is seen in this undated handout photo released to Reuters on June 1, 2012.
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